// AC M00014 XX ID F$REPCAR1_01 XX DT 13.11.92 (created); ewi. XX NA rCAR1 XX DE repressor of CAR1 expression XX BF T00726; repressor of CAR1 expression; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 2 3 3 4 N 02 5 2 2 3 N 03 2 5 4 4 N 04 1 0 2 12 T 05 14 0 0 1 A 06 2 0 13 0 G 07 0 15 0 0 C 08 0 15 0 0 C 09 2 0 12 1 G 10 0 14 1 0 C 11 0 13 2 0 C 12 5 2 7 1 R 13 10 2 2 1 A 14 6 3 5 1 N 15 6 2 7 0 R 16 4 4 5 1 N 17 4 5 4 1 N XX BA 15 elements; 1 repressing element (CAR1 gene) and 14 homologous BA binding sites XX CC compiled sequences XX RN [1] RA Luche R. M., Sumrada R., Cooper T. G. RT A cis-acting element present in multiple genes serves RT as a repressor protein binding site for the yeast CAR1 gene RL Mol. Cell. Biol. 10:3884-3895 (1990). XX // AC M00015 XX ID F$ABF1_01 XX DT 16.11.92 (created); ewi. DT 16.10.95 (updated); ewi. XX NA ABF1 XX DE ARS binding factor 1 XX BF T00056; BAF1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 7 6 3 7 N 02 6 10 4 4 N 03 13 0 4 7 W 04 4 6 4 10 N 05 15 0 9 0 R 06 0 0 1 23 T 07 1 23 0 0 C 08 18 0 5 1 A 09 0 10 0 14 Y 10 1 3 4 16 T 11 11 4 3 6 N 12 4 4 1 15 T 13 13 2 4 5 A 14 6 5 5 8 N 15 24 0 0 0 A 16 0 24 0 0 C 17 0 0 24 0 G 18 10 0 6 8 N 19 12 3 5 4 N 20 9 5 3 6 N 21 6 7 6 4 N 22 7 4 2 10 N XX BA 24 identified genomic binding sites for ABF1-related factors XX CC compiled sequences XX RN [1] RA Della Seta F., Treich I., Buhler J.-M., Sentenac A. RT ABF1 binding sites in yeast RNA polymerase genes RL J. Biol. Chem. 265:15168-15175 (1990). XX // AC M00029 XX ID F$HSF_01 XX DT 18.10.94 (created); ewi. DT 16.10.95 (updated); ewi. XX NA HSF XX DE heat shock factor (yeast) XX BF T00385; HSTF; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 28 6 12 4 A 02 0 0 48 2 G 03 46 0 2 2 A 04 46 0 2 2 A 05 12 19 8 11 N XX BA 50 functional genomic HSEs XX CC the matrix only describes the properties of the basic 5-bp unit CC of which three have to be present to constitute a minimal HSE; CC not included are sequences with more than 2 mismatches at positions 2 to 4 XX RN [1] RA Fernandes M., Xiao H., Lis J. T. RT Fine structure analyses of the Drosophila and Saccharomyces RT heat shock factor-heat shock element interactions RL Nucleic Acids Res. 22:167-173 (1994). XX // AC M00030 XX ID F$MATA1_01 XX DT 18.10.94 (created); ewi. DT 16.10.95 (updated); ewi. XX NA MATa1 XX DE mating factor a1 XX BF T00488; MATa1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 0 1 1 12 T 02 0 0 14 0 G 03 14 0 0 0 A 04 0 0 0 14 T 05 0 0 14 0 G 06 1 2 0 11 T 07 10 0 3 1 A 08 6 2 4 2 N 09 5 4 1 4 N 10 2 1 1 10 T XX BA a1 half-sites of 14 hsg operators of 4 genes XX CC compiled sequences XX RN [1] RA Goutte C., Johnson A. D. RT Recognition of a DNA operator by a dimer composed RT of two different homeodomain proteins RL EMBO J. 13:1434-1442 (1994). XX // AC M00031 XX ID F$MATALPHA2_01 XX DT 18.10.94 (created); ewi. DT 16.10.95 (updated); ewi. XX NA MATalpha2 XX DE mating factor alpha2 XX BF T00487; MATalpha2; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 2 2 3 7 N 02 2 10 1 1 C 03 8 1 4 1 R 04 1 1 0 12 T 05 0 0 13 1 G 06 0 1 0 13 T 07 5 3 2 4 N 08 7 2 2 3 N 09 7 1 0 6 W 10 6 3 1 4 N XX BA alpha2 half-sites of 14 hsg operators of 4 genes XX CC compiled sequences XX RN [1] RA Goutte C., Johnson A. D. RT Recognition of a DNA operator by a dimer composed RT of two different homeodomain proteins RL EMBO J. 13:1434-1442 (1994). XX // AC M00038 XX ID F$GCN4 XX DT 12.04.95 (created); ewi. XX NA GCN4 XX DE GCN4 XX BF T00321; GCN4; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 4 6 2 2 N 02 2 7 5 1 S 03 7 6 2 3 N 04 2 7 9 2 S 05 3 6 6 8 N 06 5 4 10 6 N 07 5 11 7 4 N 08 4 12 9 5 N 09 6 9 11 11 N 10 19 6 15 2 R 11 0 0 0 43 T 12 0 0 43 0 G 13 43 0 0 0 A 14 0 43 0 0 C 15 2 0 0 41 T 16 1 42 0 0 C 17 43 0 0 0 A 18 1 11 5 26 T 19 12 16 2 8 N 20 4 14 13 3 S 21 12 10 4 8 N 22 6 9 11 7 N 23 7 10 4 10 N 24 4 8 11 5 N 25 5 10 6 6 N 26 8 7 3 7 N 27 6 7 4 6 N XX BA 43 selected GCN4-binding sites XX CC oligonucleotides were affinity-selected on a GCN4-column containing CC bacterially expressed factor XX RN [1] RA Oliphant A. R., Brandl C. J., Struhl K. RT Defining the sequence specificity of DNA-binding proteins RT by selecting binding sites from random-sequence oligonucleotides: RT analysis of yeast GCN4 protein RL Mol. Cell. Biol. 9:2944-2949 (1989). XX // AC M00046 XX ID F$GCR1_01 XX DT 12.04.95 (created); ewi. XX NA GCR1 XX DE GCR1 XX BF T00322; GCR1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 2 0 4 0 R 02 1 0 4 1 G 03 0 6 0 0 C 04 1 0 0 5 T 05 0 0 0 6 T 06 0 6 0 0 C 07 0 6 0 0 C 08 3 0 0 3 W 09 1 4 1 0 C XX BA 6 genomic binding sites from 5 genes XX CC proven by gel shift assays XX RN [1] RA Huie M. A., Scott E. W., Drazinic C. M., Lopez M. RA C., Hornstra I. K., Yang T. P., Baker H. V. RT Characterization of the DNA-binding activity of GCR1: RT In vivo evidence for two GCR1-binding sites in the RT upstream activating sequence of TPI of Saccharomyces cerevisiae RL Mol. Cell. Biol. 12:2690-2700 (1992). XX // AC M00048 XX ID F$ADR1_01 XX DT 12.04.95 (created); ewi. DT 16.10.95 (updated); ewi. XX NA ADR1 XX DE alcohol dehydrogenase gene regulator 1 XX BF T00011; ADR1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 3 5 2 6 N 02 0 0 16 0 G 03 0 0 16 0 G 04 6 0 10 0 R 05 0 0 15 0 G 06 0 1 3 4 K XX BA 16 selected binding sequences XX CC random octameric oligonucleotides with fixed flanks bound to CC bacterially synthesized ADR1 XX RN [1] RA Cheng C., Kacherovsky N., Dombek K. M., Camier S., RA Thukral S. K., Rhim E., Young E. T. RT Identification of potential target genes for Adr1p RT through characterization of essential nucleotides in UAS1 RL Mol. Cell. Biol. 14:3842-3852 (1994). XX // AC M00049 XX ID F$GAL4_01 XX DT 13.04.95 (created); ewi. XX NA GAL4 XX DE GAL4 XX BF T00302; GAL4; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 1 5 3 2 N 02 5 2 1 3 N 03 3 2 1 5 N 04 1 10 0 0 C 05 0 0 10 1 G 06 0 1 10 0 G 07 4 3 3 1 N 08 1 3 4 3 N 09 2 4 4 1 N 10 7 0 2 2 A 11 1 8 2 0 C 12 4 1 0 6 W 13 1 3 5 2 N 14 0 2 1 8 T 15 1 6 2 2 C 16 1 5 4 1 S 17 2 1 1 7 T 18 0 10 1 0 C 19 0 11 0 0 C 20 0 0 11 0 G 21 8 0 0 3 A 22 7 0 4 0 R 23 2 6 3 0 S XX BA 11 genomic binding sites from 6 genes XX CC compiled sequences XX RN [1] RA Bram R. J., Lue N. F., Kornberg R. D. RT A GAL family of upstream activating sequences in yeast: RT roles in both induction and repression of transcription RL EMBO J. 5:603-608 (1986). XX // AC M00061 XX ID F$MIG1_01 XX DT 13.04.95 (created); hiwi. XX NA MIG1 XX DE MIG1 XX BF T00509; MIG1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 1 1 6 6 K 02 8 2 1 3 A 03 6 3 1 4 N 04 7 0 2 5 W 05 7 0 0 7 W 06 9 0 0 5 W 07 9 0 0 5 W 08 10 0 2 2 A 09 2 3 1 8 T 10 0 7 7 0 S 11 0 6 0 8 Y 12 0 0 14 0 G 13 0 0 14 0 G 14 0 0 14 0 G 15 0 0 14 0 G 16 5 1 2 6 W 17 7 2 3 2 N XX BA 14 binding sites out of 11 genes XX CC compiled sequences XX RN [1] RA Lundin M., Nehlin J. O., Ronne H. RT Importance of a flanking AT-rich region in target RT site recognition by the GC box-binding zinc finger protein MIG1 RL Mol. Cell. Biol. 14:1979-1985 (1994). XX // AC M00064 XX ID F$PHO4_01 XX DT 13.04.95 (created); hiwi. XX NA PHO4 XX DE PHO4 XX BF T00690; PHO4; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 1 2 1 4 N 02 3 2 2 1 N 03 2 3 3 0 N 04 0 8 0 0 C 05 8 0 0 0 A 06 0 8 0 0 C 07 0 0 8 0 G 08 0 0 0 8 T 09 0 0 5 3 K 10 0 2 4 2 N 11 1 0 5 2 G 12 2 2 2 2 N XX BA 8 binding sites from 4 genes XX CC compiled sequences XX RN [1] RA Fisher F., Goding C. R. RT Single amino acid substitutions alter helix--loop--helix RT protein specificity for bases flanking the core CANNTG motif RL EMBO J. 11:4103-4109 (1992). XX // AC M00125 XX ID F$MCM1_01 XX DT 22.05.95 (created); hiwi. DT 25.06.97 (updated); ewi. XX NA MCM1 XX DE yeast factor MCM1 cooperating with MATalpha factors XX BF T00500; MCM1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 8 3 2 10 W 02 3 4 4 12 T 03 6 0 5 12 W 04 0 23 0 0 C 05 0 23 0 0 C 06 0 10 0 13 Y 07 18 1 1 3 A 08 19 0 1 3 A 09 11 0 0 12 W 10 5 10 4 4 N 11 8 4 6 5 N 12 5 0 18 0 G 13 1 0 21 1 G 14 6 2 0 15 T 15 14 6 2 1 A 16 15 0 2 6 A XX BA 23 selected binding sequences XX CC 4 rounds of selection / amplification using in vitro transcribed/translated CC MCM1(1-112)T XX RN [1] RA Wynne J., Treisman R. RT SRF and MCM1 have related but distinct DNA binding specificities RL Nucleic Acids Res. 20:3297-3303 (1992). XX // AC M00154 XX ID F$STRE_01 XX DT 08.06.95 (created); hiwi. DT 18.10.95 (updated); ewi. XX NA STRE XX DE stress-response element XX P0 A C G T 01 3 3 1 10 T 02 6 7 1 3 M 03 17 0 0 0 A 04 0 0 17 0 G 05 0 0 17 0 G 06 0 0 17 0 G 07 0 0 17 0 G 08 4 5 7 1 N XX BA 17 stress-response element-related sequences from 7 stress-induced BA yeast genes XX CC compiled sequences XX RN [1] RA Schueller C., Brewster J. L., Alexander M. R., Gustin M. C., Ruis H. RT The HOG pathway controls osmotic regulation of transcription RT via the stress response element (STRE) of the Saccharomyces RT cerevisiae CTT1 gene RL EMBO J. 13:4382-4389 (1994). XX // AC M00167 XX ID F$HSF_02 XX DT 22.06.95 (created); ewi. DT 18.10.95 (updated); ewi. XX NA HSF XX DE heat shock factor (yeast) XX BF T00385; HSTF; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 28 6 12 4 A 02 0 0 48 2 G 03 46 0 2 2 A 04 46 0 2 2 A 05 12 19 8 11 N 06 28 6 12 4 A 07 0 0 48 2 G 08 46 0 2 2 A 09 46 0 2 2 A 10 12 19 8 11 N 11 28 6 12 4 A 12 0 0 48 2 G 13 46 0 2 2 A 14 46 0 2 2 A 15 12 19 8 11 N XX BA 50 functional genomic HSEs XX CC triple repeat of the 5-bp unit (M00029) in NGAANNGAANNGAAN orientation XX RN [1] RA Fernandes M., Xiao H., Lis J. T. RT Fine structure analyses of the Drosophila and Saccharomyces RT heat shock factor-heat shock element interactions RL Nucleic Acids Res. 22:167-173 (1994). XX // AC M00168 XX ID F$HSF_03 XX DT 22.06.95 (created); ewi. DT 18.10.95 (updated); ewi. XX NA HSF XX DE heat shock factor (yeast) XX BF T00385; HSTF; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 28 6 12 4 A 02 0 0 48 2 G 03 46 0 2 2 A 04 46 0 2 2 A 05 12 19 8 11 N 06 28 6 12 4 A 07 0 0 48 2 G 08 46 0 2 2 A 09 46 0 2 2 A 10 12 19 8 11 N 11 11 8 19 12 N 12 2 2 0 46 T 13 2 2 0 46 T 14 2 48 0 0 C 15 4 12 6 28 T XX BA 50 functional genomic HSEs XX CC 50 functional genomic HSEstriple repeat of the 5-bp unit (M00029) CC in NGAANNGAANNTTCN orientation XX RN [1] RA Fernandes M., Xiao H., Lis J. T. RT Fine structure analyses of the Drosophila and Saccharomyces RT heat shock factor-heat shock element interactions RL Nucleic Acids Res. 22:167-173 (1994). XX // AC M00169 XX ID F$HSF_04 XX DT 22.06.95 (created); ewi. DT 18.10.95 (updated); ewi. XX NA HSF XX DE heat shock factor (yeast) XX BF T00385; HSTF; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 28 6 12 4 A 02 0 0 48 2 G 03 46 0 2 2 A 04 46 0 2 2 A 05 12 19 8 11 N 06 11 8 19 12 N 07 2 2 0 46 T 08 2 2 0 46 T 09 2 48 0 0 C 10 4 12 6 28 T 11 28 6 12 4 A 12 0 0 48 2 G 13 46 0 2 2 A 14 46 0 2 2 A 15 12 19 8 11 N XX BA 50 functional genomic HSEs XX CC triple repeat of the 5-bp unit (M00029) in NGAANNTTCNNGAAN orientation XX RN [1] RA Fernandes M., Xiao H., Lis J. T. RT Fine structure analyses of the Drosophila and Saccharomyces RT heat shock factor-heat shock element interactions RL Nucleic Acids Res. 22:167-173 (1994). XX // AC M00170 XX ID F$HSF_05 XX DT 22.06.95 (created); ewi. DT 18.10.95 (updated); ewi. XX NA HSF XX DE heat shock factor (yeast) XX BF T00385; HSTF; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 11 8 19 12 N 02 2 2 0 46 T 03 2 2 0 46 T 04 2 48 0 0 C 05 4 12 6 28 T 06 28 6 12 4 A 07 0 0 48 2 G 08 46 0 2 2 A 09 46 0 2 2 A 10 12 19 8 11 N 11 28 6 12 4 A 12 0 0 48 2 G 13 46 0 2 2 A 14 46 0 2 2 A 15 12 19 8 11 N XX BA 50 functional genomic HSEs XX CC triple repeat of the 5-bp unit (M00028) in NTTCNNGAANNGAAN orientation XX RN [1] RA Fernandes M., Xiao H., Lis J. T. RT Fine structure analyses of the Drosophila and Saccharomyces RT heat shock factor-heat shock element interactions RL Nucleic Acids Res. 22:167-173 (1994). XX // AC M00197 XX ID F$ABF_C XX DT 05.09.95 (created); dbo. DT 29.10.96 (updated); ewi. XX NA ABF1 XX DE transcriptional activator binding to ARS sequences XX BF T00056; BAF1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 3.20 4.03 3.02 4.99 N 02 9.97 0.00 5.26 0.00 R 03 0.00 0.00 0.00 15.24 T 04 0.00 15.24 0.00 0.00 C 05 10.54 0.65 2.34 1.70 A 06 0.00 8.13 0.00 7.10 Y 07 1.45 1.63 2.95 9.20 T 08 6.11 3.56 2.40 3.17 N 09 2.52 2.99 2.28 7.45 N 10 6.94 4.02 1.87 2.42 N 11 5.85 1.92 3.93 3.53 N 12 15.24 0.00 0.00 0.00 A 13 0.00 15.24 0.00 0.00 C 14 0.00 0.00 15.24 0.00 G 15 5.83 0.00 3.21 5.36 W XX BA total weight of sequences: 15.24 XX CC consind generated matrix (random_expectation: 0.17) XX // AC M00198 XX ID F$GAL4_C XX DT 05.09.95 (created); dbo. DT 30.11.95 (updated); ewi. XX NA GAL4 XX DE GAL4 XX BF T00302; GAL4; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 1.49 1.56 0.80 5.97 T 02 0.69 9.85 0.00 0.00 C 03 0.00 0.00 10.53 0.00 G 04 0.00 0.94 9.60 0.00 G 05 4.79 2.36 2.51 0.87 N 06 1.66 3.36 3.92 1.60 N 07 3.24 4.32 2.17 0.80 N 08 5.64 0.00 2.68 2.21 A 09 1.52 7.43 1.58 0.00 C 10 3.31 0.00 0.00 7.22 T 11 0.80 3.21 4.09 2.43 N 12 0.00 2.55 0.80 7.19 T 13 0.78 5.62 2.52 1.62 C 14 0.00 4.72 3.17 2.65 N 15 1.62 0.87 2.39 5.66 T 16 0.00 9.66 0.87 0.00 C 17 0.00 10.53 0.00 0.00 C 18 0.00 0.00 10.53 0.00 G 19 6.73 0.00 0.97 2.84 A 20 5.93 0.00 3.89 0.72 R 21 2.52 6.34 0.87 0.00 C 22 2.52 0.78 5.52 1.72 G XX BA total weight of sequences: 10.53 XX CC consind generated matrix (random_expectation: 0.04) XX // AC M00199 XX ID V$AP1_C XX DT 05.09.95 (created); dbo. DT 26.09.96 (updated); ewi. XX NA AP-1 XX DE AP-1 binding site XX BF T00027; AP-1; Species: clawed frog, Xenopus. BF T00028; AP-1; Species: yeast, Saccharomyces cerevisiae. BF T00029; AP-1; Species: human, Homo sapiens. BF T00030; AP-1; Species: monkey, Cercopithecus aethiops. BF T00031; AP-1; Species: rat, Rattus norvegicus. BF T00032; AP-1; Species: mouse, Mus musculus. BF T01115; AP-1; Species: hamster. BF T01132; AP-1; Species: fruit fly, Drosophila melanogaster. BF T01140; AP-1; Species: chick, Gallus gallus. BF T01156; AP-1; Species: gibbon ape, Hylobates lar. XX P0 A C G T 01 4.79 2.30 3.06 1.30 N 02 0.00 0.00 0.00 12.15 T 03 0.00 0.00 9.83 2.32 G 04 11.28 0.00 0.00 0.87 A 05 1.28 4.71 6.16 0.00 S 06 0.00 0.00 0.00 12.15 T 07 1.46 10.70 0.00 0.00 C 08 12.15 0.00 0.00 0.00 A 09 0.89 1.22 5.91 2.17 G XX BA total weight of sequences: 12.15 XX CC consind generated matrix (random_expectation: 1.08) XX // AC M00204 XX ID F$GCN4_C XX DT 05.09.95 (created); dbo. DT 30.11.95 (updated); ewi. XX NA GCN4 XX DE GCN4 XX BF T00321; GCN4; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 2.69 2.46 1.74 0.81 N 02 5.18 0.00 2.52 0.00 A 03 4.30 0.00 2.43 0.97 R 04 0.00 0.00 0.00 7.70 T 05 0.00 0.00 7.70 0.00 G 06 7.70 0.00 0.00 0.00 A 07 0.00 6.01 0.00 1.68 C 08 0.00 0.00 0.00 7.70 T 09 0.00 7.70 0.00 0.00 C 10 3.40 1.65 0.00 1.88 W XX BA total weight of sequences: 7.70 XX CC consind generated matrix (random_expectation: 0.22) XX // AC M00207 XX ID F$LAC9_C XX DT 05.09.95 (created); dbo. DT 30.11.95 (updated); ewi. XX NA LAC9 XX DE LAC9 binding site XX BF T00458; LAC9; Species: yeast, Kluyveromyces lactis. XX P0 A C G T 01 0.87 1.68 1.86 1.84 N 02 0.00 0.00 0.00 6.26 T 03 0.93 0.93 0.00 0.00 M 04 0.84 0.00 1.87 3.55 K 05 0.00 6.26 0.00 0.00 C 06 0.00 0.00 6.26 0.00 G 07 0.00 0.00 6.26 0.00 G 08 4.48 0.90 0.87 0.00 A 09 3.58 0.90 0.00 1.77 A 10 0.93 1.75 0.93 2.65 N 11 3.52 0.00 0.00 2.74 W 12 0.00 4.39 0.00 1.86 C 13 0.84 0.00 0.00 4.51 T 14 0.00 0.84 2.80 2.62 K 15 0.00 2.55 0.90 2.80 Y 16 2.59 0.87 1.86 0.94 N 17 1.68 2.71 1.86 0.00 N 18 0.94 0.00 0.00 5.32 T 19 0.00 6.26 0.00 0.00 C 20 0.00 6.26 0.00 0.00 C 21 0.00 0.90 5.35 0.00 G 22 1.86 0.94 1.75 1.71 N XX BA total weight of sequences: 6.26 XX CC consind generated matrix (random_expectation: < 0.01) XX // AC M00213 XX ID F$RAP1_C XX DT 05.09.95 (created); dbo. DT 30.11.95 (updated); ewi. XX NA RAP1 XX DE yeast repressor/activator protein 1 XX BF T00715; RAP1; Species: yeast, Saccharomyces cerevisiae. XX P0 A C G T 01 6.89 2.40 0.79 4.74 W 02 8.80 0.00 4.58 1.43 R 03 7.20 6.83 0.79 0.00 M 04 14.82 0.00 0.00 0.00 A 05 0.00 14.82 0.00 0.00 C 06 0.00 14.82 0.00 0.00 C 07 0.00 14.82 0.00 0.00 C 08 14.82 0.00 0.00 0.00 A 09 2.13 0.67 2.87 9.15 T 10 11.92 0.76 1.49 0.64 A 11 0.76 14.06 0.00 0.00 C 12 11.45 3.36 0.00 0.00 A 13 0.79 5.64 0.00 7.10 Y 14 1.64 7.18 1.61 4.39 Y XX BA total weight of sequences: 14.82 XX CC consind generated matrix (random_expectation: 0.03) XX