:>"^‹ã@s.dZddlZdd„Zdd„ZdS)zLocal Composition Complexity.éNcCsƒtjdƒ}t|ƒ}y|jƒ}Wn$tk rQt|ƒjƒ}YnXdg}dg}xNt|ƒD]@}|j|dt|ƒtj|dt|ƒƒ|ƒqqW|d|…}|j dƒ} |j dƒ} |j dƒ} |j dƒ} || } || }|| }|| }|j| ||| ƒ|d}x/t||ƒD]}||d||d…}||dkr¤|j|d ƒnÍ|dkr˜| d8} |j dƒr| d7} || } || }|j| ||| ƒqq|j dƒrN| d7} || } || }|j| ||| ƒqq|j dƒrq| d7} || } || }|j| ||| ƒnÙ|dkrŒ| d8} |j dƒrø| d7} || } || }|j| ||| ƒqq|j dƒrB| d7} || }|| }|j| ||| ƒqq|j dƒrq| d7} || }|| }|j| ||| ƒnå|dkr€| d8} |j dƒrì| d7} || } || }|j| ||| ƒqq|j dƒr6| d7} || }|| }|j| ||| ƒqq|j dƒrq| d7} || }|| }|j| ||| ƒnñ|dkrq| d8} |j dƒrà| d7} || } || }|j| ||| ƒn‘|j dƒr*| d7} || }|| }|j| ||| ƒnG|j dƒrq| d7} || }|| }|j| ||| ƒ|d}q^W|S) aÚCalculate Local Composition Complexity (LCC) values over sliding window. Returns a list of floats, the LCC values for a sliding window over the sequence. seq - an unambiguous DNA sequence (a string or Seq object) wsize - window size, integer The result is the same as applying lcc_simp multiple times, but this version is optimized for speed. The optimization works by using the value of previous window as a base to compute the next one. éréÚAÚCÚTÚGéÿÿÿÿr) ÚmathÚlogÚlenÚupperÚAttributeErrorÚstrÚrangeÚappendÚfloatÚcountÚendswith)ÚseqÚwsizeÚl2Ztamseqr ZcomponeZlccsalÚiZwindowZcant_aZcant_cZcant_tZcant_gÚterm_aÚterm_cÚterm_tÚterm_gÚtailÚx©rú5/tmp/pip-build-ww9dw3qa/biopython/Bio/SeqUtils/lcc.pyÚlcc_mult sÀ     8                                                 r c Cs«t|ƒ}y|jƒ}Wn$tk rBt|ƒjƒ}YnXtjdƒ}d|krgd}n=|jdƒt|ƒtj|jdƒt|ƒƒ|}d|kr¹d}n=|jdƒt|ƒtj|jdƒt|ƒƒ|}d|kr d}n=|jdƒt|ƒtj|jdƒt|ƒƒ|}d|kr]d}n=|jdƒt|ƒtj|jdƒt|ƒƒ|}|||| S)abCalculate Local Composition Complexity (LCC) for a sequence. seq - an unambiguous DNA sequence (a string or Seq object) Returns the Local Composition Complexity (LCC) value for the entire sequence (as a float). Reference: Andrzej K Konopka (2005) Sequence Complexity and Composition https://doi.org/10.1038/npg.els.0005260 rrrrrr)r r r rr r rr)rrr rrrrrrrrÚlcc_simps.    '  '  '  'r!)Ú__doc__r r r!rrrrÚs  r